Research progress on fiber-based laser sources for coherent Raman scattering imaging
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1.Academy for Engineering and Technology, State Key Laboratory of Surface Physics and Department of Physics, Yiwu Research Institute, Human Phenome Institute, Key Laboratory of Micro and Nano Photonic Structures(Ministry of Education), Fudan University, Shanghai 200433, China;2.The School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

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Supported by the National Natural Science Foundation of China(62425501)

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    Abstract:

    Coherent Raman scattering microscopy is widely regarded as a powerful tool for solving biomedical problems due to its chemical specificity, label-free imaging capability, high spectral resolution and high sensitivity. However, the clinical application of coherent Raman scattering imaging technology has long been hindered by environmental sensitivity and large volume solid-state lasers. Ultrafast fiber lasers, with their compactness and stability, can effectively overcome these shortcomings. In this paper, different realization methods and research progress of fiber-based laser sources in coherent Raman scattering imaging are reviewed, including supercontinuum fiber source, soliton self-frequency shift fiber source, fiber optical parametric oscillator and synchronized fiber source, and the future development is prospected.

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History
  • Received:March 19,2025
  • Revised:April 13,2025
  • Adopted:April 16,2025
  • Online: April 17,2025
  • Published:
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